Perkins Eastman, in a joint venture with Rafael Viñoly Architects, designed the Perelman Center for Advanced Medicine. The new ambulatory care center is a functional practice and training site for physicians, medical students, and researchers. The building maximizes the site’s development potential through thoughtful integration of inspiring design and flexible spaces and accommodates future needs with modular, organized interiors. A transparent central public atrium serves as the focal point for the building’s entrance, providing a venue for public functions and serving as the primary vertical circulation. The exterior perimeter of U-shaped clinical spaces surrounding the atrium maximizes daylight potential and affords public spaces, waiting areas, clinical spaces, and offices the benefit of extensive natural light and views. The first phase of the Center includes the Abramson Cancer Center, cardiovascular, dermatology, endoscopy, executive health and lung center services, and an eight-OR ambulatory surgery center. A radiation oncology center includes five linear accelerators, with MRI, CT, and PET/CT simulation. The diagnostic imaging area includes six MRIs, four CTs, two PET CTs, two Gamma Cameras, 10 mammography units, and an invasive cardiology laboratory.